I’ve currently updated one of my NC installations from 22.2.0 to 22.2.1. After this update the complete performance of the web server went worse by factors, changing between apps i.e. takes several seconds (which was immediately with 22.2.0).
I’ve rolled back my Snapshot to 22.2.0 and all was fine.
I found an already opened Github issued by another user here, so I’m not the only guy seeing issues: 22.2.1 is very slow · Issue #29678 · nextcloud/server · GitHub
I’m currently retesting … just want to issue a warning to you guys to not update your production cloud without having a proper snapshot to roll back. For me, 22.2.1 was absolute unusable due to this issue (Ubuntu 20.04 LTS, 8GB RAM, 12 vCPU, Apache, PHP-FPM 7.4.25).