Long time to start download file from nextcloud with browser

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I have trouble with using NC on web. If i try to download any file by web version NC, i need wait a lot time for starting refresh page and start download. If I use for example android app nextcloud - any file start download from my NC at moment.

Nextcloud version (eg, 18.0.2): 18.0.4
Operating system and version (eg, Ubuntu 20.04):18.04
Apache or nginx version (eg, Apache 2.4.25): Apache 2.4.41
PHP version (eg, 7.1): 7.3.13

The issue you are facing:
If i to do any with file my interface and page responce very slow. On system I see when i try download large file, that my average load CPU more than 1.2(sometimes >2). For example:
file size 594,8Mb clicking to download, page response for starting download ~ 85sec,
file size 2,2Gb clicking to download, page response for starting download ~ 180sec.
My NC live on VMware, storage 500Gb, 2 core Intel® Xeon® CPU X5650 @ 2.67GHz, 4 RAM. I’m disable a lot apps, my tests after reboot server and with 1 active user have same results.

Is this the first time you’ve seen this error? (Y/N): Yes

The output of your config.php file in /path/to/nextcloud (make sure you remove any identifiable information!):

'auth.bruteforce.protection.enabled' => true,
  'blacklisted_files' => 
  array (
    0 => '.htaccess',
    1 => 'Thumbs.db',
    2 => 'thumbs.db',
  ),
  'cron_log' => true,
  'enable_previews' => true,
  'enabledPreviewProviders' => 
  array (
    0 => 'OC\\Preview\\PNG',
    1 => 'OC\\Preview\\JPEG',
    2 => 'OC\\Preview\\GIF',
    3 => 'OC\\Preview\\BMP',
    4 => 'OC\\Preview\\XBitmap',
    5 => 'OC\\Preview\\Movie',
    6 => 'OC\\Preview\\PDF',
    7 => 'OC\\Preview\\MP3',
    8 => 'OC\\Preview\\TXT',
    9 => 'OC\\Preview\\MarkDown',
  ),
  'filesystem_check_changes' => 0,
  'filelocking.enabled' => 'true',
  'htaccess.RewriteBase' => '/',
  'integrity.check.disabled' => false,
  'knowledgebaseenabled' => false,
  'logfile' => '/var/nc_data/nextcloud.log',
  'loglevel' => 2,
  'logtimezone' => 'Europe/Berlin',
  'log_rotate_size' => 104857600,
  'maintenance' => false,
  'memcache.local' => '\\OC\\Memcache\\APCu',
'memcache.locking' => '\\OC\\Memcache\\Redis',
  'overwriteprotocol' => 'https',
  'preview_max_x' => 1024,
  'preview_max_y' => 768,
  'preview_max_scale_factor' => 1,
  'redis' => 
  array (
    'host' => '/var/run/redis/redis-server.sock',
    'port' => 0,
    'timeout' => 0.0,
  ),
  'quota_include_external_storage' => false,
  'share_folder' => '/Shares',
  'skeletondirectory' => '',
  'theme' => '',
  'trashbin_retention_obligation' => 'auto, 7',
  'updater.release.channel' => 'stable',
  'ldapIgnoreNamingRules' => false,
  'ldapProviderFactory' => 'OCA\\User_LDAP\\LDAPProviderFactory',
  'app_install_overwrite' => 
  array (
    0 => 'nextant',
  ),
  'updater.secret' => '$2y$10$J6vFIo814u9ybYyPqnhQleVw7U541fUWx00THjIJXPGlv/ma',
);

The output of your Apache/nginx/system log in /var/log/____: this part of access.log apache2, when I’m press download file 2.2Gb in 21:31.

x.x.x.x - - [27/Dec/2019:21:31:14 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 593 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:14 +0000] "GET /csrftoken HTTP/2.0" 200 143 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:15 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 163 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:16 +0000] "GET /apps/files/?dir=/&fileid=709 HTTP/2.0" 303 102 "-" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:16 +0000] "GET /apps/files/?dir=/ HTTP/2.0" 200 8379 "-" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:16 +0000] "GET /apps/accessibility/js/accessibility?v=0 HTTP/2.0" 200 207 "https://site.name/apps/files/?dir=/" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:16 +0000] "GET /css/icons/icons-vars.css?v=1577477979 HTTP/2.0" 200 27805 "https://site.name/apps/files/?dir=/" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:16 +0000] "GET /apps/theming/js/theming?v=2 HTTP/2.0" 200 431 "https://site.name/apps/files/?dir=/" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:16 +0000] "GET /avatar/94812DDD-A769-411D-A56C-49B1534AE412/64?v=1 HTTP/2.0" 304 98 "https://site.name/apps/files/?dir=/" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:16 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 140 "https://site.name/apps/files/?dir=/" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:17 +0000] "GET /ocs/v2.php/core/whatsnew?format=json HTTP/2.0" 204 57 "https://site.name/apps/files/?dir=/" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:17 +0000] "GET /apps/encryption/ajax/getStatus HTTP/2.0" 200 340 "https://site.name/apps/files/?dir=/" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:17 +0000] "GET /avatar/94812DDD-A769-411D-A56C-49B1534AE412/88?v=1 HTTP/2.0" 304 76 "https://site.name/apps/files/?dir=/" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:17 +0000] "PROPFIND /remote.php/dav/files/94812DDD-A769-411D-A56C-49B1534AE412/ HTTP/2.0" 207 5532 "https://site.name/apps/files/?dir=/" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:17 +0000] "GET /index.php/apps/files/ajax/getstoragestats.php?dir=%2F HTTP/2.0" 200 393 "https://site.name/apps/files/?dir=/" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:18 +0000] "GET /apps/theming/manifest?v=2 HTTP/2.0" 200 1112 "https://site.name/apps/files/?dir=/" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:46 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 163 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:32:16 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 163 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:32:47 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 163 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:33:17 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 163 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:33:47 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 163 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:34:17 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 163 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:34:46 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 559 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:31:22 +0000] "GET /remote.php/webdav/VMware-VIM-all-6.5.0-7312210.iso HTTP/2.0" 200 1109234376 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:35:17 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 593 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:35:47 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 593 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"
x.x.x.x - - [27/Dec/2019:21:36:30 +0000] "GET /ocs/v2.php/apps/notifications/api/v2/notifications HTTP/2.0" 200 593 "https://site.name/apps/files/?dir=/&fileid=709" "Mozilla/5.0 (Linux; Android 10.0; Redmi K20 Pro) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/79.0.3945.93 Mobile Safari/537.36"