Sorry, but I don’t understand your reason to do that. But first, this seems impossible because there are several Programs who are pointing to that folder.
Read this.
But if you are low on space, you can expand the virtual Drive using Windows Server Tools (and a couple of commands at Linux), or you can add the Drives of the Host by using the APP external Drives.
This is another way, to have more space i.e. syncing Data
https://help.ubuntu.com/community/Partitioning/Home/Moving