Hi!
I did this about a month ago and it’s worked great since then. See my post here: Is the Linux desktop client reliable? - #14 by dms
I think there is a bug with the sync clients (not just the Linux client?) where they don’t respect the per-share ignore list. I had luck adding items to the global ignore (Settings > Advanced > Edit Ignored Files).
Make sure to ignore .local/share/Nextcloud, otherwise the client will infinitely update its status (in that directory), sync the updated status, update the status again, sync the status again, etc. I also ignored .local/share/Trash.
Also, I chose to sync only key folders within ~, because I wanted to keep the option to have local-only files and server-only files. Something to think about, depending how you see your usage growing.
Good luck to you!
Dan