High-performance backend truenas scale nextcloud talk can’t connect

why is you signal server in trusted domains?

this seems to be pointing to your issue. looks like its not proxied correctly and has no valid certificate.
is signal internet facing and forwarded to a valid encrypted domain https://your.signal.domain.tld?

also double check

Allow inbound bypass for TURN & STUN on port 3478 tcp/udp which must be internet facing in router/firewall (i.e your.domain.tld:3478)

be aware, that the above example is a standalone docker service! consider requesting assistance from the truenas folks.