Finished install and config, the server return a 404 error

im using a platform by centos7,nginx 1.19.1, php7.4.8,mysql 8.0.20
and following the config by

when i access the domain name of nextcloud server, that return a 404 error, and the nginx log showing:
2020/07/23 04:17:10 [error] 11476#0: *1273 open() “/usr/local/nginx/html/index.php/login” failed (20: Not a directory), client:, server: localhost, request: “GET /index.php/login HTTP/1.1”, host: “

what’s problem with the server…?