Configuring MariaDB Database when Using Docker

The latest NextCloud documentation has an updated section regarding database configuration, however I am not sure on how to apply these settings when using Docker. In the section relating to MySQL/MariaDB it is mentioned that the /etc/mysql/my.cnf could look like this:

skip_name_resolve = 1
innodb_buffer_pool_size = 128M
innodb_buffer_pool_instances = 1
innodb_flush_log_at_trx_commit = 2
innodb_log_buffer_size = 32M
innodb_max_dirty_pages_pct = 90
query_cache_type = 1
query_cache_limit = 2M
query_cache_min_res_unit = 2k
query_cache_size = 64M
tmp_table_size= 64M
max_heap_table_size= 64M
slow_query_log = 1
slow_query_log_file = /var/log/mysql/slow.log
long_query_time = 1

!includedir /etc/mysql/conf.d/
!includedir /etc/mysql/mariadb.conf.d/

default-character-set = utf8mb4

character_set_server = utf8mb4
collation_server = utf8mb4_general_ci
transaction_isolation = READ-COMMITTED
binlog_format = ROW

Does that mean that these are the recommended settings and should be added to/updated in the default database configuration? Are they independent of system/setup? And if not how should they be tuned based on the system?

I am using the mariadb:10.5 image for my database Docker container. The default configuration under /etc/mysql/my.cnf in the container looks like this:

# The MariaDB configuration file
# The MariaDB/MySQL tools read configuration files in the following order:
# 0. "/etc/mysql/my.cnf" symlinks to this file, reason why all the rest is read.
# 1. "/etc/mysql/mariadb.cnf" (this file) to set global defaults,
# 2. "/etc/mysql/conf.d/*.cnf" to set global options.
# 3. "/etc/mysql/mariadb.conf.d/*.cnf" to set MariaDB-only options.
# 4. "~/.my.cnf" to set user-specific options.
# If the same option is defined multiple times, the last one will apply.
# One can use all long options that the program supports.
# Run program with --help to get a list of available options and with
# --print-defaults to see which it would actually understand and use.
# If you are new to MariaDB, check out

# This group is read both by the client and the server
# use it for options that affect everything
# Port or socket location where to connect
# port = 3306
socket = /run/mysqld/mysqld.sock

# Import all .cnf files from configuration directory

!includedir /etc/mysql/mariadb.conf.d/
!includedir /etc/mysql/conf.d/

It is missing a lot of the settings listed in the documentation example. Should I add the settings to this file? Will they not be reset once I reboot the container?

When checking the database variables on a clean instance of a MariaDB container I find that some of the variables from the NextCloud example are already default. Still I am unsure if the NextCloud example are actually recommended settings for a NextCloud setup or f it is just a general example.