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Sorry to hear you’re facing problems 
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In order to help you as quickly as possible, before clicking Create Topic please provide as much of the below as you can. Feel free to use a pastebin service for logs, otherwise either indent short log examples with four spaces:
example
Or for longer, use three backticks above and below the code snippet:
longer
example
here
Some or all of the below information will be requested if it isn’t supplied; for fastest response please provide as much as you can 
Nextcloud version :15.0.
Operating system and version :18.04.01
Apache or nginx version :apache 2.4
PHP version :7.2
The issue you are facing: Cannot upload files bigger than 10MB through Desktop APP. No problem with web GUI, get error message that “Connection is closed” by server
The output of your Nextcloud log in Admin > Logging:
nothing visible, no logs from server present
The output of your config.php file in /path/to/nextcloud (make sure you remove any identifiable information!):
<?php
$CONFIG = array (
'instanceid' => '',
'passwordsalt' => 'xxxx',
'secret' => '',
'trusted_domains' =>
array (
0 => '',
1 => 'own.xxxxx.de',
),
'datadirectory' => '/media/storage1/owncloud',
'overwrite.cli.url' => 'http://xx.xxxxx/nextcloud',
'dbtype' => 'mysql',
'version' => '15.0.2.0',
'dbname' => 'nextcloud',
'dbhost' => 'localhost',
'dbtableprefix' => 'oc_',
'dbuser' => 'nc',
'dbpassword' => 'xxxxxx',
'logtimezone' => 'Europe/Berlin',
'logfile' => '/var/www/nextcloud/data/nextcloud.log',
'loglevel' => 3,
'syslog_tag' => 'Nextcloud',
'log_rotate_size' => '104857600',
'installed' => true,
'theme' => '',
'session_keepalive' => true,
'maintenance' => false,
'trashbin_retention_obligation' => 'auto',
'mail_from_address' => 'server',
'mail_smtpmode' => 'smtp',
'mail_domain' => 'xxxxx',
'mail_smtpauthtype' => 'LOGIN',
'mail_smtpauth' => 1,
'mail_smtphost' => 'xxxx',
'mail_smtpport' => '25',
'mail_smtpname' => xxxx',
'mail_smtppassword' => 'xxxxx',
'updater.release.channel' => 'stable',
'filelocking.enabled' => 'true',
'memcache.local' => '\\OC\\Memcache\\Redis',
'memcache.locking' => '\\OC\\Memcache\\Redis',
'redis' =>
array (
'host' => '/var/run/redis/redis-server.sock',
'port' => 0,
'timeout' => 0.0,
),
);
The output of your Apache/nginx/system log in /var/log/____:
PASTE HERE
