AH01071: Got error 'Primary script unknown'

Nextcloud version: 18.0.4
Operating system and version: debian buster
Apache version: 2.4.38
PHP version: 7.3

The issue you are facing:
I get a lot of these error messages in my /var/log/apache2/error.log:
[Wed Apr 29 22:37:58.378124 2020] [proxy_fcgi:error] [pid 14589:tid 140106925074176] [client my_ip_address:53030] AH01071: Got error ‘Primary script unknown’

Is this the first time you’ve seen this error?
I get it every day with many entries. I searched the nextcloud help etc. but could not solve this by myself. I read that it might be due to some bodged rewrite rules.

Steps to replicate it:

  1. run nextcloud with apache2 server
  2. get a lot of messages in the error.log

I suspect some rewrite rule to cause this:

My .htaccess file in document root looks like this:

<IfModule mod_rewrite.c>
  RewriteEngine on
  RewriteRule ^\.well-known/host-meta /nextcloud/public.php?service=host-meta [QSA,L]
  RewriteRule ^\.well-known/host-meta\.json /nextcloud/public.php?service=host-meta-json [QSA,L]
  RewriteRule ^\.well-known/webfinger /nextcloud/public.php?service=webfinger [QSA,L]
  RewriteRule ^\.well-known/carddav /nextcloud/remote.php/dav/ [R=301,L]
  RewriteRule ^\.well-known/caldav /nextcloud/remote.php/dav/ [R=301,L]
  RedirectMatch ^/$ /nextcloud/
</IfModule>

The last lines in my /var/www/nextcloud/.htaccess look like this:

#### DO NOT CHANGE ANYTHING ABOVE THIS LINE ####

ErrorDocument 403 /nextcloud/
ErrorDocument 404 /nextcloud/
<IfModule mod_rewrite.c>
  Options -MultiViews
  RewriteRule ^core/js/oc.js$ index.php [PT,E=PATH_INFO:$1]
  RewriteRule ^core/preview.png$ index.php [PT,E=PATH_INFO:$1]
  RewriteCond %{REQUEST_FILENAME} !\.(css|js|svg|gif|png|html|ttf|woff2?|ico|jpg|jpeg|map|webm|mp4)$
  RewriteCond %{REQUEST_FILENAME} !core/img/favicon.ico$
  RewriteCond %{REQUEST_FILENAME} !core/img/manifest.json$
  RewriteCond %{REQUEST_FILENAME} !/remote.php
  RewriteCond %{REQUEST_FILENAME} !/public.php
  RewriteCond %{REQUEST_FILENAME} !/cron.php
  RewriteCond %{REQUEST_FILENAME} !/core/ajax/update.php
  RewriteCond %{REQUEST_FILENAME} !/status.php
  RewriteCond %{REQUEST_FILENAME} !/ocs/v1.php
  RewriteCond %{REQUEST_FILENAME} !/ocs/v2.php
  RewriteCond %{REQUEST_FILENAME} !/robots.txt
  RewriteCond %{REQUEST_FILENAME} !/updater/
  RewriteCond %{REQUEST_FILENAME} !/ocs-provider/
  RewriteCond %{REQUEST_FILENAME} !/ocm-provider/
  RewriteCond %{REQUEST_URI} !^/\.well-known/(acme-challenge|pki-validation)/.*
  RewriteRule . index.php [PT,E=PATH_INFO:$1]
  RewriteBase /nextcloud
  <IfModule mod_env.c>
    SetEnv front_controller_active true
    <IfModule mod_dir.c>
      DirectorySlash off
    </IfModule>
  </IfModule>
</IfModule>

This keeps happening. Can somebody help?