Very strange. See what I got when not commenting the setting:
And it works perfectly fine without here. Which version of coTURN do you use? Perhaps this changed and it was/is even required on older versions.
Okay, so if inbound 5349 (+80/443) and outbound everything is open and you still don’t get a connection I am also out of ideas. But since it works without iptables, you know where to tinker around. netstat shows the established connections, it would be interesting to see the blocked connections (by iptables).