PHP APCu OPcache not configured

Nextcloud 13.0.1.
Fedora 27 Server
Apache/2.4.33 (Fedora)
PHP Version: 7.2.4

After updating php to 7.2.4 from 7.1.16 and setting my local memcache to PHP APCu

'memcache.locking' => '\\OC\\Memcache\\Redis',
'memcache.local' => '\\OC\\Memcache\\APCu',

I’m running into this error on the admin page:

The PHP OPcache is not properly configured. For better performance it is recommended to use the following settings in the php.ini:
opcache.enable=1
opcache.enable_cli=1
opcache.interned_strings_buffer=8
opcache.max_accelerated_files=10000
opcache.memory_consumption=128
opcache.save_comments=1
opcache.revalidate_freq=1

My 10-opcache.ini (/etc/php.d/10-opcache.ini) config:

; Enable Zend OPcache extension module
zend_extension=opcache.so

; Determines if Zend OPCache is enabled
opcache.enable=1

; Determines if Zend OPCache is enabled for the CLI version of PHP
opcache.enable_cli=1

; The OPcache shared memory storage size.
opcache.memory_consumption=128

; The amount of memory for interned strings in Mbytes.
opcache.interned_strings_buffer=8

; The maximum number of keys (scripts) in the OPcache hash table.
; Only numbers between 200 and 1000000 are allowed.
opcache.max_accelerated_files=10000

; The maximum percentage of "wasted" memory until a restart is scheduled.
;opcache.max_wasted_percentage=5

; When this directive is enabled, the OPcache appends the current working
; directory to the script key, thus eliminating possible collisions between
; files with the same name (basename). Disabling the directive improves
; performance, but may break existing applications.
;opcache.use_cwd=1

; When disabled, you must reset the OPcache manually or restart the
; webserver for changes to the filesystem to take effect.
;opcache.validate_timestamps=1

; How often (in seconds) to check file timestamps for changes to the shared
; memory storage allocation. ("1" means validate once per second, but only
; once per request. "0" means always validate)
opcache.revalidate_freq=1

; Enables or disables file search in include_path optimization
;opcache.revalidate_path=0

; If disabled, all PHPDoc comments are dropped from the code to reduce the
; size of the optimized code.
opcache.save_comments=1

; If enabled, a fast shutdown sequence is used for the accelerated code
; Depending on the used Memory Manager this may cause some incompatibilities.
;opcache.fast_shutdown=0

; Allow file existence override (file_exists, etc.) performance feature.
;opcache.enable_file_override=0

; A bitmask, where each bit enables or disables the appropriate OPcache
; passes
;opcache.optimization_level=0xffffffff

;opcache.inherited_hack=1
;opcache.dups_fix=0

; The location of the OPcache blacklist file (wildcards allowed).
; Each OPcache blacklist file is a text file that holds the names of files
; that should not be accelerated.
opcache.blacklist_filename=/etc/php.d/opcache*.blacklist

; Allows exclusion of large files from being cached. By default all files
; are cached.
;opcache.max_file_size=0

; Check the cache checksum each N requests.
; The default value of "0" means that the checks are disabled.
;opcache.consistency_checks=0

; How long to wait (in seconds) for a scheduled restart to begin if the cache
; is not being accessed.
;opcache.force_restart_timeout=180

; OPcache error_log file name. Empty string assumes "stderr".
;opcache.error_log=

; All OPcache errors go to the Web server log.
; By default, only fatal errors (level 0) or errors (level 1) are logged.
; You can also enable warnings (level 2), info messages (level 3) or
; debug messages (level 4).
;opcache.log_verbosity_level=1

; Preferred Shared Memory back-end. Leave empty and let the system decide.
;opcache.preferred_memory_model=

; Protect the shared memory from unexpected writing during script execution.
; Useful for internal debugging only.
;opcache.protect_memory=0

; Allows calling OPcache API functions only from PHP scripts which path is
; started from specified string. The default "" means no restriction
;opcache.restrict_api=

; Enables and sets the second level cache directory.
; It should improve performance when SHM memory is full, at server restart or
; SHM reset. The default "" disables file based caching.
; RPM note : file cache directory must be owned by process owner
;   for mod_php, see /etc/httpd/conf.d/php.conf
;   for php-fpm, see /etc/php-fpm.d/*conf
;opcache.file_cache=

; Enables or disables opcode caching in shared memory.
;opcache.file_cache_only=0

; Enables or disables checksum validation when script loaded from file cache.
;opcache.file_cache_consistency_checks=1

; Implies opcache.file_cache_only=1 for a certain process that failed to
; reattach to the shared memory (for Windows only). Explicitly enabled file
; cache is required.
;opcache.file_cache_fallback=1

; Validate cached file permissions.
; Leads OPcache to check file readability on each access to cached file.
; This directive should be enabled in shared hosting environment, when few
; users (PHP-FPM pools) reuse the common OPcache shared memory.
;opcache.validate_permission=0

; Prevent name collisions in chroot'ed environment.
; This directive prevents file name collisions in different "chroot"
; environments. It should be enabled for sites that may serve requests in
; different "chroot" environments.
;opcache.validate_root=0

; Enables or disables copying of PHP code (text segment) into HUGE PAGES.
; This should improve performance, but requires appropriate OS configuration.
opcache.huge_code_pages=1

This only occurred after I switched \OC\Memcache\APCu.

I have that config in

/etc/php/7.1/mods-available/opcache.ini

(still runnung php7.1). This is a Debian system.

@umu did you try

grep -r "^opcache" /etc/*

to find all appearance of opcache entries in any ini. and then check if one of the variables nc is complaining about is defined twice.

and/or

php --ini

to see which ini files php is using. (but this are only the ini files the cli version of php is using.