No input file specified. Permission denied

Hello since today, i can´t open Nextcloud anymore.
I got the Message No input file specified when i open the Browser. The Nginx log tells me no Permission to open index.php. But Nginx User is www-data and chown is correct.

No idea what happen. Yesterday it works fine. Other Websites on this Server works correct.

[/details]

groups www-data

www-data : www-data redis

Nextcloud version (eg, 20.0.5): 22.2.0
Operating system and version (eg, Ubuntu 20.04): Debian 11
Apache or nginx version (eg, Apache 2.4.25): Nginx 1.18.0
PHP version (eg, 7.4): 8.0

The issue you are facing:

Is this the first time you’ve seen this error? (Y/N): Y

The output of your Nextcloud log in Admin > Logging:

PASTE HERE

The output of your config.php file in /path/to/nextcloud (make sure you remove any identifiable information!):

<?php
$CONFIG = array (
  'instanceid' => 'oc6n3y7swbbw',
  'passwordsalt' => 'somePassword',
  'secret' => 'somePassword',
  'trusted_domains' => 
  array (
    0 => 'cloud.domain.tld',
  ),
  'datadirectory' => '/home/ncdata/data',
  'dbtype' => 'mysql',
  'version' => '22.2.0.2',
  'overwrite.cli.url' => 'https://cloud.domain.tld',
  'dbname' => 'nextcloud',
  'dbhost' => 'localhost',
  'dbport' => '',
  'dbtableprefix' => 'oc_',
  'mysql.utf8mb4' => true,
  'dbuser' => 'cloud',
  'dbpassword' => 'U2GX7iXZYtgGNBm8dhRkhE',
  'installed' => true,
  'theme' => '',
  'loglevel' => 0,
  'default_phone_region' => 'DE',
  'maintenance' => false,
  'filesystem_check_changes' => 1,
  'has_rebuilt_cache' => true,
  'memcache.local' => '\OC\Memcache\APCu',
  'memcache.locking' => '\\OC\\Memcache\\Redis',
  'memcache.distributed' => '\\OC\\Memcache\\Redis',
  'redis' => 
  array (
    'host' => '127.0.0.1',
    'port' => '6379',
    'password' => 'somePassword',
  ),
  'app_install_overwrite' => 
  array (
    0 => 'previewgenerator',
  ),
);

The output of your Apache/nginx/system log in /var/log/____:

2021/10/25 09:11:20 [error] 4082325#4082325: *5115693 FastCGI sent in stderr: "Unable to open primary script: /var/www/cloud/index.php (Operation not permitted)" while reading response header from upstream, client: 213.246.38.133, server: cloud.domain.tld, request: "GET /apps/social/@lars HTTP/1.1", upstream: "fastcgi://unix:/var/run/php/php8.0-fpm.sock:", host: "cloud.domain.tld"