OK, that could be the problem:
run
sudo a2dismod php8.1
sudo systemctl reload apache2
Then it should work.
I did that. No difference.
When I stop php7.4-fpm, Nextcloud again is down 
How did you stop it?
Since it is already disabled.
Have you tried restart apache2 and php8.1-fpm (not just reload) or reboot if nothing works?
I don’t know!
I have disabled it, RESTARTed apache2, but it is still running and in use.
ps -ef| fgrep -i php-fpm.
root 107484 1 0 15:47 ? 00:00:01 php-fpm: master process (/etc/php/8.1/fpm/php-fpm.conf)
root 114947 1 0 18:34 ? 00:00:00 php-fpm: master process (/etc/php/7.4/fpm/php-fpm.conf)
And what php-version is shown on the server info page in:
https://[yourcloud.com]/settings/admin/serverinfo
Version: 7.4.33
Try
tail -f /var/log/apache2/error.log
and then run
sudo systemctl reload apache2
Look what it says.
I would just uninstall everything to PHP7.4 (apt-get remove ...). Does not belong to the release you are using anyway. And then I would look for a guide on how to configure Nextcloud, where it explains exactly how to configure php-fpm.
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I think that, if you haven’t already done it, you should modify the apache configuration file for you domain under /etc/apache2/sistes-enabled/yourdomain.org.conf and change the php version for the SetHandler variable.
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I agree above will solve it.
if not it’s a .htaccess issue
Thank You all for Your support.
I will check it next week and let You know.
Thank You Alessandro! That did the trick 
Great! Now you have some extra tools to help someone else solve the same problem.
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