Modify MariaDB directives

Today i checked my MaridDB configuration file (50-server.cnf) and compared them with the nextcloud recommendations.

I found some missing settings.

Now i have to add or change the following directives:

[mysqld]

transaction_isolation = READ-COMMITTED
binlog_format = ROW
skip-name-resolve
innodb_flush_log_at_trx_commit = 2
innodb_log_buffer_size = 32M
innodb_max_dirty_pages_pct = 90

Can these settings be set retrospectively without great risk?

Br

fettfoen