External storage for main file

Is it possible to make external storage for the main file storing. So its not seperated folder at the main file, and make it diffrent for each user like the main storage because i have seperate hosts for the web and storage.

You can use external storage for primary storage.

https://docs.nextcloud.com/server/19/admin_manual/configuration_files/primary_storage.html

I think you also can use e.g. NFS.