Client file sync errors

So Im running NextCloud on CentOS 7 and Im having some issues with syncing with the sync client. It will randomly struggle to upload large files (100 mb and larger). No relevant errors in the apache log or the nginx reverse proxy server, and I think I’ve nailed it down to the following errors listed in the Nextcloud log.

unlink(/var/www/html/nextcloud/data/eho/cache/test.mp4-chunking-4048613850-8): No such file or directory at /var/www/html/nextcloud/lib/private/Files/Storage/Local.php#230

Im using APCu for local caching and redis for file locking. Config.php is left as default with the following additions:

'memcache.local' => '\OC\Memcache\APCu',
  'memcache.locking' => '\OC\Memcache\Redis',
  'redis' => array(
     'host' => 'localhost',
     'port' => 6379,

Any ideas?

For larger files, the client breaks the files into chunks and uploads them separately into the cache-folder. Can you check on this cache folder (/var/www/html/nextcloud/data/eho/cache) if you see any files during the upload?
If you try, just use some files a bit larger (~150-500 MB), beyond 2 GB there is a different class of errors.